Charles Eugène Espidon Goupil (December 14, 1831 – October 24, 1896) was a French Mexican philanthropist and collector.
In 1889 he bought Joseph Marius Alexis Aubin's collection of 384 Mesoamerican manuscripts. On May 14, 1864, he married Augustine Élie. After Goupil's death, his wife donated the collection to the Bibliothèque Nationale in Paris.
Goupil was the great-uncle of artist Jean Charlot.